ZnT49B Zinc transporter 49B [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ZnT49Bprovided by FlyBase
Official Full Name: Zinc transporter 49Bprovided by FlyBase
Primary source: FLYBASE:FBgn0033762
Locus tag: Dmel_CG8632
See related: AllianceGenome:FB:FBgn0033762
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: cg8632; CG8632; Dmel\CG8632; dZnT49B; ZNT49B
Summary: Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transport. Predicted to be located in mitochondrial membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including adult head; embryonic/larval midgut; germline cell; gonad; and pole plasm. Orthologous to human SLC30A9 (solute carrier family 30 member 9). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (12652805..12655743)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (8540310..8543248)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables zinc ion transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in intracellular zinc ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in zinc ion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in zinc ion transport	IEA Inferred from Electronic Annotation more info
involved_in zinc ion transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain