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    CG10257 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36671, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10257provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033985
    Locus tag
    Dmel_CG10257
    See related
    AllianceGenome:FB:FBgn0033985
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH51312; Dmel\CG10257
    Summary
    Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Is expressed in eye. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10257 in Genome Data Viewer
    Location:
    51D5-51D5; 2-73 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14942398..14944469)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10829903..10831974)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Alkylglycerone phosphate synthase Neighboring gene uncharacterized protein Neighboring gene Lap1 Neighboring gene atypical protein kinase C Neighboring gene caskin Neighboring gene transfer RNA:Leucine-AAG 1-1 Neighboring gene parcas

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster. Bogaerts-Márquez M, et al. Mol Ecol, 2021 Feb. PMID 33350518, Free PMC Article
    2. Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. Huylmans AK, et al. G3 (Bethesda), 2014 Sep 22. PMID 25246242, Free PMC Article
    3. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article
    4. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. Xu H, et al. EMBO J, 2004 Feb 25. PMID 14963491, Free PMC Article
    5. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10257-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14942398..14944469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137164.4 → NP_611008.2  uncharacterized protein Dmel_CG10257 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611008.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SWZ6
      Related
      FBpp0086539
      Conserved Domains (1) summary
      pfam06905
      Location:34 → 208
      FAIM1; Fas apoptotic inhibitory molecule (FAIM1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SWZ6 Q8SWZ6

    Gene LinkOut

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