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    CG7194 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38933, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7194provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035868
    Locus tag
    Dmel_CG7194
    See related
    AllianceGenome:FB:FBgn0035868
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:CK00048; BEST:CK01174; ck00048; CK01174; Dmel\CG7194
    Summary
    Involved in copper ion homeostasis. Is expressed in adult head. Orthologous to human CGAS (cyclic GMP-AMP synthase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7194 in Genome Data Viewer
    Location:
    66C5-66C5; 3-24 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8302364..8304059, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8295464..8297159, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rab19 Neighboring gene ADP-ribosylation factor-like 5 Neighboring gene uncharacterized protein Neighboring gene SECIS-binding protein 2 Neighboring gene Gustatory receptor 66a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two cGAS-like receptors induce antiviral immunity in Drosophila. Holleufer A, et al. Nature, 2021 Sep. PMID 34261128
    2. Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function. Martin M, et al. Cell Rep, 2018 Jun 19. PMID 29924997, Free PMC Article
    3. Multiple Niche Compartments Orchestrate Stepwise Germline Stem Cell Progeny Differentiation. Tu R, et al. Curr Biol, 2021 Feb 22. PMID 33357404, Free PMC Article
    4. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. Zheng Y, et al. BMC Genomics, 2011 Dec 6. PMID 22145623, Free PMC Article
    5. A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Kopczynski CC, et al. Proc Natl Acad Sci U S A, 1998 Aug 18. PMID 9707585, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables 2',3'-cyclic GMP-AMP synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in copper ion homeostasis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7194-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8302364..8304059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139946.2 → NP_648203.1  uncharacterized protein Dmel_CG7194 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648203.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VSH0
      Related
      FBpp0076437
      Conserved Domains (1) summary
      pfam03281
      Location:59 → 317
      Mab-21; Mab-21 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSH0.1 Q9VSH0

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