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    Cpr66D Cuticular protein 66D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38990, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr66Dprovided by FlyBase
    Official Full Name
    Cuticular protein 66Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052029
    Locus tag
    Dmel_CG32029
    See related
    AllianceGenome:FB:FBgn0052029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32029; CG6458; CG6469; DmelCpr66D; Dmel\CG32029
    Summary
    A structural constituent of eye lens. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in several structures, including adult head; embryonic epipharynx; embryonic head epidermis; embryonic hypopharynx; and embryonic/larval tracheal dorsal trunk. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr66D in Genome Data Viewer
    Location:
    66D9-66D9; 3-26 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8640439..8643584)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8633539..8636684)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sperm-Leucylaminopeptidase 2 Neighboring gene GTPase activating protein, SECIS-dependent read-through Neighboring gene Z band alternatively spliced PDZ-motif protein 66 Neighboring gene Cell division cycle 6 Neighboring gene uncharacterized protein Neighboring gene Peroxin 7 Neighboring gene Arrestin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cuticular nature of corneal lenses in Drosophila melanogaster. Stahl AL, et al. Dev Genes Evol, 2017 Jul. PMID 28477155, Free PMC Article
    2. Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects. Knudsen KE, et al. G3 (Bethesda), 2020 Apr 9. PMID 32019873, Free PMC Article
    3. Transcriptome analysis of Drosophila suzukii reveals molecular mechanisms conferring pyrethroid and spinosad resistance. Tabuloc CA, et al. Sci Rep, 2024 Aug 27. PMID 39191909, Free PMC Article
    4. Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease. Xun Z, et al. Mol Cell Proteomics, 2008 Jul. PMID 18353766, Free PMC Article
    5. Insights into aging through measurements of the Drosophila proteome as a function of temperature. Robinson RA, et al. Mech Ageing Dev, 2010 Sep. PMID 20732347, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables structural constituent of eye lens IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cuticular protein 66D
    Names
    CG32029-PA
    Cpr66D-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8640439..8643584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168288.3 → NP_729400.1  cuticular protein 66D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729400.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYI5, Q9VSN3
      Related
      FBpp0076294
      Conserved Domains (1) summary
      pfam00379
      Location:158 → 210
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSN3 Q9VSN3

    Gene LinkOut

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