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    CG11619 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40072, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11619provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036836
    Locus tag
    Dmel_CG11619
    See related
    AllianceGenome:FB:FBgn0036836
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11619
    Summary
    Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Orthologous to human GPCPD1 (glycerophosphocholine phosphodiesterase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11619 in Genome Data Viewer
    Location:
    75F2-75F2; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18985905..18988323, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18979005..18981423, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45689 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tis11 mediated mRNA decay promotes the reacquisition of Drosophila intestinal stem cell quiescence. McClelland L, et al. Dev Biol, 2017 Jun 1. PMID 28445691, Free PMC Article
    2. Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of Drosophila melanogaster. Baker BM, et al. Proc Natl Acad Sci U S A, 2021 Jun 8. PMID 34074789, Free PMC Article
    3. Dietary cysteine drives body fat loss via FMRFamide signaling in Drosophila and mouse. Song T, et al. Cell Res, 2023 Jun. PMID 37055592, Free PMC Article
    4. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article
    5. New levels of transcriptome complexity at upper thermal limits in wild Drosophila revealed by exon expression analysis. Telonis-Scott M, et al. Genetics, 2013 Nov. PMID 24002645, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glycerophosphocholine phosphodiesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables starch binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycerophospholipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11619-PA
    NP_649081.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18985905..18988323 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140824.2 → NP_649081.1  uncharacterized protein Dmel_CG11619 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649081.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVV4
      Related
      FBpp0074813
      Conserved Domains (3) summary
      cd05814
      Location:69 → 196
      CBM20_Prei4; Prei4, N-terminal CBM20 (carbohydrate-binding module, family 20) domain. Preimplantation protein 4 (Prei4) is a protein of unknown function that is expressed during mouse preimplantation embryogenesis. In addition to the N-terminal CBM20 domain, Prei4 ...
      cd08607
      Location:361 → 648
      GDPD_GDE5; Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins
      pfam03009
      Location:366 → 649
      GDPD; Glycerophosphoryl diester phosphodiesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVV4 Q9VVV4

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