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    CG9449 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40117, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9449provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036875
    Locus tag
    Dmel_CG9449
    See related
    AllianceGenome:FB:FBgn0036875
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9449
    Summary
    Predicted to enable acid phosphatase activity. Predicted to be located in extracellular exosome and nucleus. Is expressed in amnioserosa; embryonic/larval salivary gland; and yolk nucleus. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Orthologous to human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9449 in Genome Data Viewer
    Location:
    76B5-76B5; 3-45 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19492053..19497723, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19485153..19490823, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene brivido-1 Neighboring gene hairpin RNA:CR33940 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. Drnevich JM, et al. Proc Biol Sci, 2004 Nov 7. PMID 15539352, Free PMC Article
    2. Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Sieber MH, et al. Curr Biol, 2015 Apr 20. PMID 25802149, Free PMC Article
    3. The Hippo pathway promotes cell survival in response to chemical stress. Di Cara F, et al. Cell Death Differ, 2015 Sep. PMID 26021298, Free PMC Article
    4. A genomic response to the yeast transcription factor GAL4 in Drosophila. Liu Y, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820459, Free PMC Article
    5. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acid phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9449-PE
    CG9449-PF
    CG9449-PG
    CG9449-PH
    CG9449-PJ
    CG9449-PK
    NP_001137975.1
    NP_001137976.1
    NP_001262047.1
    NP_001262048.1
    NP_001262049.2
    NP_001287119.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19492053..19497723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275119.1 → NP_001262048.1  uncharacterized protein Dmel_CG9449, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262048.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z080
      Conserved Domains (1) summary
      cd07061
      Location:48 → 348
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

    2. NM_001275118.1 → NP_001262047.1  uncharacterized protein Dmel_CG9449, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262047.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z080
      Conserved Domains (1) summary
      cd07061
      Location:48 → 348
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

    3. NM_001144504.2 → NP_001137976.1  uncharacterized protein Dmel_CG9449, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137976.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z080
      Conserved Domains (1) summary
      cd07061
      Location:48 → 348
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

    4. NM_001275120.2 → NP_001262049.2  uncharacterized protein Dmel_CG9449, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262049.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCZ1
      Conserved Domains (1) summary
      cd07061
      Location:35 → 335
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

    5. NM_001144503.2 → NP_001137975.1  uncharacterized protein Dmel_CG9449, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137975.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z082
      Conserved Domains (1) summary
      cd07061
      Location:48 → 169
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

    6. NM_001300190.1 → NP_001287119.1  uncharacterized protein Dmel_CG9449, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287119.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JBA7
      Conserved Domains (1) summary
      cd07061
      Location:35 → 156
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z080 B7Z080
    B7Z082 B7Z082
    M9PCZ1 M9PCZ1
    Q8SY04 Q8SY04
    X2JBA7 X2JBA7

    Gene LinkOut

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