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    glob2 globin 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40807, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glob2provided by FlyBase
    Official Full Name
    globin 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0250846
    Locus tag
    Dmel_CG15180
    See related
    AllianceGenome:FB:FBgn0250846
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-SAGE:Wang-121; CG15180; DmeGb2; Dmel\CG15180; Glob2
    Summary
    Predicted to enable heme binding activity and oxygen binding activity. Predicted to be located in nucleus. Is expressed in early elongation stage spermatid; onion stage spermatid; organism; primary spermatocyte; and secondary spermatocyte. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See glob2 in Genome Data Viewer
    Location:
    83F4-83F4; 3-47.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6605997..6608914, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2431719..2434636, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene solwind

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Globin Gene Family in Arthropods: Evolution and Functional Diversity. Prothmann A, et al. Front Genet, 2020. PMID 32922435, Free PMC Article
    2. Testes-specific hemoglobins in Drosophila evolved by a combination of sub- and neofunctionalization after gene duplication. Gleixner E, et al. BMC Evol Biol, 2012 Mar 19. PMID 22429626, Free PMC Article
    3. Divergent roles of the Drosophila melanogaster globins. Burmester T, et al. J Insect Physiol, 2018 Apr. PMID 28606854
    4. The hemoglobin genes of Drosophila. Burmester T, et al. FEBS J, 2006 Feb. PMID 16420471
    5. Proteomic analysis of individual fruit fly hemolymph. Zeng Q, et al. J Chromatogr B Analyt Technol Biomed Life Sci, 2015 Feb 15. PMID 25596379

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    globin 2
    Names
    CG15180-PB
    CG15180-PC
    CG15180-PD
    anon-SAGE:Wang-121
    glob2-PB
    glob2-PC
    glob2-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6605997..6608914 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275392.2 → NP_001262321.1  globin 2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262321.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H8F4P7
      Conserved Domains (1) summary
      cd01040
      Location:61 → 161
      Mb_like; myoglobin_like; M family globin domain

    2. NM_001275393.1 → NP_001262322.1  globin 2, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262322.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGM9
      Conserved Domains (1) summary
      cd01040
      Location:61 → 148
      Mb_like; myoglobin_like; M family globin domain

    3. NM_141412.3 → NP_649669.3  globin 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649669.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6L1, Q9VI36
      Conserved Domains (1) summary
      cd01040
      Location:61 → 161
      Mb_like; myoglobin_like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGM9 A0A0B4KGM9
    H8F4P7 H8F4P7
    Q4V6L1 Q4V6L1

    Gene LinkOut

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