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    CG5281 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41375, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5281provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037902
    Locus tag
    Dmel_CG5281
    See related
    AllianceGenome:FB:FBgn0037902
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5281
    Summary
    Predicted to enable antiporter activity and nucleotide-sugar transmembrane transporter activity. Predicted to be involved in nucleotide-sugar transmembrane transport. Predicted to be active in membrane. Orthologous to human SLC35G1 (solute carrier family 35 member G1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5281 in Genome Data Viewer
    Location:
    86E5-86E5; 3-51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11435850..11437523)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7261572..7263245)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L24-like Neighboring gene D-aminoacyl-tRNA deacylase Neighboring gene uncharacterized protein Neighboring gene Exonuclease 3'-5' domain-containing 2 Neighboring gene uncharacterized protein Neighboring gene sarcomere length short Neighboring gene mir-4945 stem loop Neighboring gene Peptidoglycan recognition protein LB

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nishihara T, et al. Nucleic Acids Res, 2013 Oct. PMID 23863838, Free PMC Article
    2. Deadenylation is a widespread effect of miRNA regulation. Eulalio A, et al. RNA, 2009 Jan. PMID 19029310, Free PMC Article
    3. The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila. Han Y, et al. Elife, 2017 Aug 14. PMID 28806173, Free PMC Article
    4. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
    5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables nucleotide-sugar transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleotide-sugar transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5281-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11435850..11437523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141819.2 → NP_650076.1  uncharacterized protein Dmel_CG5281 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650076.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGN6
      Related
      FBpp0081867
      Conserved Domains (3) summary
      COG0697
      Location:38 → 328
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
      pfam00892
      Location:38 → 169
      EamA; EamA-like transporter family
      cl23754
      Location:189 → 324
      EamA; EamA-like transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGN6 Q9VGN6

    Gene LinkOut

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