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    d-cup davis-cup [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41580, updated on 9-Dec-2024

    Summary

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    Official Symbol
    d-cupprovided by FlyBase
    Official Full Name
    davis-cupprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038089
    Locus tag
    Dmel_CG14387
    See related
    AllianceGenome:FB:FBgn0038089
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14387; Dmel\CG14387
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Is expressed in elongation stage spermatid and primary spermatocyte. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human CLXN (calaxin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See d-cup in Genome Data Viewer
    Location:
    87D3-87D3; 3-53 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12891956..12893158)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8717678..8718880)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46218 Neighboring gene antisense RNA:CR44235 Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Post-meiotic transcription in Drosophila testes. Barreau C, et al. Development, 2008 Jun. PMID 18434411
    2. The genetics of egg retention and fertilization success in Drosophila: One step closer to understanding the transition from facultative to obligate viviparity. Horváth B, et al. Evolution, 2018 Feb. PMID 29265369
    3. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    davis-cup
    Names
    CG14387-PA
    d-cup-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12891956..12893158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141978.3 → NP_650235.1  davis-cup [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650235.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H0RNF5, Q9VG22
      Related
      FBpp0082151
      Conserved Domains (1) summary
      pfam13499
      Location:114 → 180
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG22 Q9VG22

    Gene LinkOut

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