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    CG34404 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41873, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34404provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085433
    Locus tag
    Dmel_CG34404
    See related
    AllianceGenome:FB:FBgn0085433
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-FF; CG18496; CG6156; Dmel\CG34404
    Old locus tag
    CG18496; CG6156; Dmel_CG18496; Dmel_CG6156
    Summary
    Predicted to be involved in establishment of protein localization. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human MCC (MCC regulator of WNT signaling pathway). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34404 in Genome Data Viewer
    Location:
    88F1-88F1; 3-57 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15363786..15367665, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11189508..11193387, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene 3-hydroxyisobutyryl-CoA hydrolase Neighboring gene Component of oligomeric golgi complex 2 Neighboring gene Translin associated factor X Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cerebral cavernous malformation 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved motif controls nuclear localization of Drosophila Muscleblind. Fernandez-Costa JM, et al. Mol Cells, 2010 Jul. PMID 20652497
    2. A transcriptional network associated with natural variation in Drosophila aggressive behavior. Edwards AC, et al. Genome Biol, 2009. PMID 19607677, Free PMC Article
    3. Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms. Still IH, et al. BMC Evol Biol, 2004 Jun 18. PMID 15207008, Free PMC Article
    4. RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models. Zhang X, et al. Heliyon, 2023 May. PMID 37251843, Free PMC Article
    5. Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Pospisilik JA, et al. Cell, 2010 Jan 8. PMID 20074523

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34404-PC
    CG34404-PE
    CG34404-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15363786..15367665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169651.4 → NP_732023.2  uncharacterized protein Dmel_CG34404, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NV7, Q9VF74, Q9VF75
      Conserved Domains (2) summary
      COG1196
      Location:451 → 651
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam10506
      Location:317 → 381
      MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

    2. NM_142199.4 → NP_650456.2  uncharacterized protein Dmel_CG34404, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650456.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KSI6, Q95TY5
      Related
      FBpp0111581
      Conserved Domains (2) summary
      pfam10506
      Location:218 → 282
      MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
      cl02005
      Location:484 → 546
      WXG100; Proteins of 100 residues with WXG

    3. NM_142200.4 → NP_650457.2  uncharacterized protein Dmel_CG34404, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650457.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NV7, Q9VF73
      Conserved Domains (3) summary
      pfam05483
      Location:99 → 599
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam10506
      Location:368 → 432
      MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
      cl02005
      Location:609 → 696
      WXG100; Proteins of 100 residues with WXG
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KSI6 Q7KSI6
    Q86NV7 Q86NV7
    Q95TY5 Q95TY5
    Q9VF73 Q9VF73
    Q9VF74 Q9VF74

    Gene LinkOut

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