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    CG42233 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43754, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42233provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0250755
    Locus tag
    Dmel_CG42233
    See related
    AllianceGenome:FB:FBgn0250755
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11574; CG2112; Dmel\CG42233
    Old locus tag
    Dmel_CG11574; Dmel_CG2112
    Summary
    Predicted to be involved in negative regulation of fatty acid biosynthetic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in organism. Orthologous to human DCAF5 (DDB1 and CUL4 associated factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42233 in Genome Data Viewer
    Location:
    100D2-100D2; 3-102 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31799634..31805278, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27625356..27631000, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene septin interacting protein 3 Neighboring gene uncharacterized protein Neighboring gene fat facets Neighboring gene Methylcrotonoyl-CoA carboxylase 1 Neighboring gene ATP-dependent chromatin assembly factor large subunit Neighboring gene Ionotropic receptor 100a Neighboring gene uncharacterized protein Neighboring gene Riboflavin transporter

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulators of autophagosome formation in Drosophila muscles. Zirin J, et al. PLoS Genet, 2015 Feb. PMID 25692684, Free PMC Article
    2. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42233-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31799634..31805278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143642.4 → NP_651899.2  uncharacterized protein Dmel_CG42233 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651899.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9T1
      Conserved Domains (3) summary
      COG2319
      Location:45 → 404
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:100 → 142
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:90 → 402
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V9T1 Q9V9T1

    Gene LinkOut

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