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    CG1965 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40842, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1965provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037466
    Locus tag
    Dmel_CG1965
    See related
    AllianceGenome:FB:FBgn0037466
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1965
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to several human genes including PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1965 in Genome Data Viewer
    Location:
    84B2-84B2; 3-48 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (7067401..7071624)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2893123..2897346)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene don juan like Neighboring gene Male-specific transcript 84B Neighboring gene uncharacterized protein Neighboring gene UFM1 specific ligase 1 Neighboring gene antisense RNA:CR45908 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Nutrient-Responsive Molecular Chaperone Hsp90 Supports Growth and Development in Drosophila. Ohhara Y, et al. Front Physiol, 2021. PMID 34239451, Free PMC Article
    2. Lack of the Drosophila BEAF insulator proteins alters regulation of genes in the Antennapedia complex. Roy S, et al. Mol Genet Genomics, 2011 Feb. PMID 21132442
    3. The Wright stuff: reimagining path analysis reveals novel components of the sex determination hierarchy in Drosophila melanogaster. Fear JM, et al. BMC Syst Biol, 2015 Sep 4. PMID 26335107, Free PMC Article
    4. Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Beckstead RB, et al. Insect Biochem Mol Biol, 2007 Jun. PMID 17517334, Free PMC Article
    5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spliceosomal complex disassembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type post-mRNA release spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of catalytic step 2 spliceosome HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1965-PA
    CG1965-PB
    CG1965-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      7067401..7071624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275396.1 → NP_001262325.1  uncharacterized protein Dmel_CG1965, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262325.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KF71
      Conserved Domains (1) summary
      PRK06647
      Location:11 → 89
      PRK06647; DNA polymerase III subunits gamma and tau; Validated

    2. NM_001260027.2 → NP_001246956.1  uncharacterized protein Dmel_CG1965, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246956.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6A9
      Conserved Domains (1) summary
      PRK06647
      Location:11 → 89
      PRK06647; DNA polymerase III subunits gamma and tau; Validated

    3. NM_141432.3 → NP_649689.1  uncharacterized protein Dmel_CG1965, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649689.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI54
      Related
      FBpp0081148
      Conserved Domains (1) summary
      pfam07842
      Location:619 → 829
      GCFC; GC-rich sequence DNA-binding factor-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K6A9 A0A0B4K6A9
    A0A0B4KF71 A0A0B4KF71
    Q8MRQ8 Q8MRQ8
    Q9VI54 Q9VI54

    Gene LinkOut

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