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    CG9313 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37374, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9313provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034566
    Locus tag
    Dmel_CG9313
    See related
    AllianceGenome:FB:FBgn0034566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9313
    Summary
    Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Involved in sensory perception of sound. Predicted to be part of outer dynein arm. Is expressed in Johnston organ neurons; chordotonal neurons; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9313 in Genome Data Viewer
    Location:
    57B5-57B5; 2-92 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20978901..20984043)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16866406..16871548)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene dim gamma-tubulin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sperm of Fruit Fly Drosophila melanogaster under Space Flight. Ogneva IV, et al. Int J Mol Sci, 2022 Jul 6. PMID 35886847, Free PMC Article
    2. A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex. Boylan K, et al. Mol Biol Cell, 2000 Nov. PMID 11071907, Free PMC Article
    3. Host adaptation to viruses relies on few genes with different cross-resistance properties. Martins NE, et al. Proc Natl Acad Sci U S A, 2014 Apr 22. PMID 24711428, Free PMC Article
    4. Environmental chemical mediated male reproductive toxicity: Drosophila melanogaster as an alternate animal model. Tiwari AK, et al. Theriogenology, 2011 Jul 15. PMID 21356551
    5. Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing. Karak S, et al. Sci Rep, 2015 Nov 26. PMID 26608786, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dynein heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dynein light chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in outer dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of outer dynein arm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of outer dynein arm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9313-PA
    CG9313-PB
    CG9313-PC
    dynein
    NP_001286656.1
    • unusual splice
    NP_611530.5
    • unusual splice

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20978901..20984043
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299727.1 → NP_001286656.1  uncharacterized protein Dmel_CG9313, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286656.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KVQ2, Q8MSJ9, Q9W2P3
      Conserved Domains (3) summary
      COG2319
      Location:352 → 705
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:361 → 411
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:412 → 639
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001299728.1 → NP_001286657.1  uncharacterized protein Dmel_CG9313, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286657.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LG18
      Conserved Domains (3) summary
      COG2319
      Location:353 → 706
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:362 → 412
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:413 → 640
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_137686.6 → NP_611530.5  uncharacterized protein Dmel_CG9313, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611530.5

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KVQ2, Q8MSJ9, Q9W2P3
      Conserved Domains (3) summary
      COG2319
      Location:352 → 705
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:361 → 411
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:412 → 639
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LG18 A0A0B4LG18
    Q8MSJ9 Q8MSJ9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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