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    CG8042 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38886, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8042provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027554
    Locus tag
    Dmel_CG8042
    See related
    AllianceGenome:FB:FBgn0027554
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.245; anon-WO0172774.24; BcDNA:GH10229; Dmel\CG8042
    Summary
    Predicted to be involved in ERAD pathway. Located in endomembrane system. Is expressed in adult head and adult heart. Used to study candidiasis. Orthologous to human UBXN4 (UBX domain protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8042 in Genome Data Viewer
    Location:
    66A21-66A21; 3-21 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7972449..7974991, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7965549..7968091, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene extra-extra Neighboring gene Ribonuclease X25 Neighboring gene uncharacterized protein Neighboring gene Heterochromatin protein 4 Neighboring gene POP4 ribonuclease P/MRP subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hip, an HP1-interacting protein, is a haplo- and triplo-suppressor of position effect variegation. Schwendemann A, et al. Proc Natl Acad Sci U S A, 2008 Jan 8. PMID 18162556, Free PMC Article
    2. A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation. Beskow A, et al. J Mol Biol, 2009 Dec 11. PMID 19782090
    3. The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Ashton-Beaucage D, et al. Cell, 2010 Oct 15. PMID 20946983
    4. A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection. Glittenberg MT, et al. Dis Model Mech, 2022 May 1. PMID 35142345, Free PMC Article
    5. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8042-PA
    UBX domain 2 like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7972449..7974991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139908.3 → NP_648165.1  uncharacterized protein Dmel_CG8042 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648165.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9Y114
      Related
      FBpp0076481
      Conserved Domains (4) summary
      pfam12446
      Location:170 → 337
      DUF3682; Protein of unknown function (DUF3682)
      cd16269
      Location:342 → 353
      GBP_C; coiled coil [structural motif]
      cl00155
      Location:399 → 476
      UBQ; Ubiquitin-like proteins
      cl20817
      Location:272 → 367
      GBP_C; Guanylate-binding protein, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y114 Q9Y114

    Gene LinkOut

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