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    beat-Ic beaten path Ic [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34945, updated on 9-Dec-2024

    Summary

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    Official Symbol
    beat-Icprovided by FlyBase
    Official Full Name
    beaten path Icprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028644
    Locus tag
    Dmel_CG4838
    See related
    AllianceGenome:FB:FBgn0028644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    beat Ic; beat-1c; beat-C; Beat-Ic; BG:DS00913.1; CG4838; CT15531; Dmel\CG4838
    Summary
    Involved in axon guidance; defasciculation of motor neuron axon; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in plasma membrane. Is expressed in adult head; lobula columnar neuron LC12; organism; and peripodial epithelium of eye disc. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See beat-Ic in Genome Data Viewer
    Location:
    35E1-35E2; 2-51 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16000291..16041703)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16000291..16041703)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43412 Neighboring gene long non-coding RNA:CR43825 Neighboring gene long non-coding RNA:CR43826 Neighboring gene long non-coding RNA:CR44844 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Bicaudal C Neighboring gene beaten path Ia Neighboring gene long non-coding RNA:CR44870

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2. Kim SH, et al. Elife, 2023 Apr 11. PMID 37039476, Free PMC Article
    2. Specification of Drosophila motoneuron identity by the combinatorial action of POU and LIM-HD factors. Certel SJ, et al. Development, 2004 Nov. PMID 15469973
    3. Asymmetric activity of NetrinB controls laterality of the Drosophila brain. Lapraz F, et al. Nat Commun, 2023 Feb 24. PMID 36828820, Free PMC Article
    4. The Beat generation: a multigene family encoding IgSF proteins related to the Beat axon guidance molecule in Drosophila. Pipes GC, et al. Development, 2001 Nov. PMID 11714679
    5. Fine scale structural variants distinguish the genomes of Drosophila melanogaster and D. pseudoobscura. Macdonald SJ, et al. Genome Biol, 2006. PMID 16872532, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: 16040641-16040682 mobile_element_type = transposon:INE-1{}2856

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defasciculation of motor neuron axon IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beaten path Ic
    Names
    CG4838-PA
    CG4838-PB
    CG4838-PC
    beat-Ic-PA
    beat-Ic-PB
    beat-Ic-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16000291..16041703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299041.1 → NP_001285970.1  beaten path Ic, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285970.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NK69, Q9VJM4
      Conserved Domains (1) summary
      cl11960
      Location:189 → 246
      Ig; Immunoglobulin domain

    2. NM_001299042.1 → NP_001285971.1  beaten path Ic, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NK69, Q9VJM4
      Conserved Domains (1) summary
      cl11960
      Location:189 → 246
      Ig; Immunoglobulin domain

    3. NM_078856.4 → NP_523580.1  beaten path Ic, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523580.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NK69, Q9VJM4
      Related
      FBpp0080359
      Conserved Domains (1) summary
      cl11960
      Location:189 → 246
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJM4 Q9VJM4

    Gene LinkOut

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