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    Snrk SNF related kinase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36579, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snrkprovided by FlyBase
    Official Full Name
    SNF related kinaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033915
    Locus tag
    Dmel_CG8485
    See related
    AllianceGenome:FB:FBgn0033915
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    152964_at; CG8485; Dmel\CG8485; SNRK
    Summary
    Predicted to enable protein serine/threonine kinase activity. Orthologous to human SNRK (SNF related kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Snrk in Genome Data Viewer
    Location:
    50E4-50E4; 2-69 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14235787..14239703, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10123292..10127208, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Optic atrophy 1 Neighboring gene mir-1016 stem loop Neighboring gene Ubiquitin specific protease 20/33 Neighboring gene SET and MYND domain containing, arthropod-specific, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization. Couderc JL, et al. PLoS One, 2017. PMID 28767695, Free PMC Article
    2. A screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defect. Shaukat Z, et al. PLoS One, 2012. PMID 23077619, Free PMC Article
    3. Cytoplasmic polyadenylation is a major mRNA regulator during oogenesis and egg activation in Drosophila. Cui J, et al. Dev Biol, 2013 Nov 1. PMID 23978535, Free PMC Article
    4. The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis. McMillan EA, et al. J Biol Chem, 2018 Feb 23. PMID 29326167, Free PMC Article
    5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SNF related kinase
    Names
    CG8485-PA
    CG8485-PB
    CG8485-PC
    Snrk-PA
    Snrk-PB
    Snrk-PC
    NP_610942.2
    NP_725370.1
    NP_725371.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14235787..14239703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137098.3 → NP_610942.2  SNF related kinase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610942.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E981, Q8SWX3
      Related
      FBpp0086695
      Conserved Domains (3) summary
      smart00220
      Location:20 → 273
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14339
      Location:296 → 338
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:16 → 273
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase

    2. NM_166041.2 → NP_725370.1  SNF related kinase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725370.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E981, Q8SWX3
      Related
      FBpp0086697
      Conserved Domains (3) summary
      smart00220
      Location:20 → 273
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14339
      Location:296 → 338
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:16 → 273
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase

    3. NM_166042.2 → NP_725371.1  SNF related kinase, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725371.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E981, Q8SWX3
      Related
      FBpp0086698
      Conserved Domains (3) summary
      smart00220
      Location:20 → 273
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14339
      Location:296 → 338
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:16 → 273
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E981 Q0E981
    Q8SWX3 Q8SWX3
    Q960G5 Q960G5

    Gene LinkOut

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