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    Tbca Tubulin binding cofactor A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43737, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tbcaprovided by FlyBase
    Official Full Name
    Tubulin binding cofactor Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039869
    Locus tag
    Dmel_CG1890
    See related
    AllianceGenome:FB:FBgn0039869
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1890; Dmel\CG1890
    Summary
    Predicted to enable tubulin binding activity. Predicted to be involved in protein folding and tubulin complex assembly. Predicted to be active in microtubule cytoskeleton. Is expressed in organism. Orthologous to human TBCA (tubulin folding cofactor A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tbca in Genome Data Viewer
    Location:
    100D2-100D2; 3-102 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31743490..31744248)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27569212..27569970)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation elongation factor 1 alpha 2 Neighboring gene uncharacterized protein Neighboring gene abnormal wing discs Neighboring gene nero

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance. Bai J, et al. Development, 2008 Apr. PMID 18359903, Free PMC Article
    2. A conceptual view at microtubule plus end dynamics in neuronal axons. Voelzmann A, et al. Brain Res Bull, 2016 Sep. PMID 27530065, Free PMC Article
    3. Signalling crosstalk at the leading edge controls tissue closure dynamics in the Drosophila embryo. Rousset R, et al. PLoS Genet, 2017 Feb. PMID 28231245, Free PMC Article
    4. Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster. Das R, et al. Genetics, 2017 Dec. PMID 29025914, Free PMC Article
    5. Single-cell RNA sequencing identifies eggplant as a regulator of germ cell development in Drosophila. Sun Z, et al. EMBO Rep, 2023 Oct 9. PMID 37603128, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in post-chaperonin tubulin folding pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tubulin complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tubulin complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tubulin binding cofactor A
    Names
    CG1890-PA
    Tbca-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31743490..31744248
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143628.3 → NP_651885.1  tubulin binding cofactor A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9U7
      Related
      FBpp0085195
      Conserved Domains (1) summary
      pfam02970
      Location:9 → 94
      TBCA; Tubulin binding cofactor A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V9U7 Q9V9U7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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