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    CG17249 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38201, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17249provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035249
    Locus tag
    Dmel_CG17249
    See related
    AllianceGenome:FB:FBgn0035249
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17249
    Summary
    Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in papillary renal cell carcinoma. Orthologous to human PRCC (proline rich mitotic checkpoint control factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17249 in Genome Data Viewer
    Location:
    62A9-62A9; 3-0.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1645931..1647464, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1645931..1647464, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Big brother Neighboring gene Coat Protein (coatomer) alpha Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45815 Neighboring gene Brother Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid β Toxicity in the Drosophila Brain. Belfiori-Carrasco LF, et al. Front Aging Neurosci, 2017. PMID 28352227, Free PMC Article
    2. Genetic Dissection of Alzheimer's Disease Using Drosophila Models. Jeon Y, et al. Int J Mol Sci, 2020 Jan 30. PMID 32019113, Free PMC Article
    3. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17249-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1645931..1647464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139381.2 → NP_647638.1  uncharacterized protein Dmel_CG17249 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647638.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0B6
      Related
      FBpp0072692
      Conserved Domains (1) summary
      pfam10253
      Location:371 → 472
      PRCC; Mitotic checkpoint regulator, MAD2B-interacting
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W0B6 Q9W0B6

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