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    CG8531 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36584, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8531provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033918
    Locus tag
    Dmel_CG8531
    See related
    AllianceGenome:FB:FBgn0033918
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8531
    Summary
    Predicted to enable ATPase activator activity. Predicted to be involved in cristae formation and protein import into mitochondrial matrix. Predicted to be located in mitochondrion and nucleus. Is expressed in several structures, including Malpighian tubule primordium; embryonic/larval midgut primordium; larval muscle cell; mesoderm; and visceral mesoderm derivative. Orthologous to human DNAJC11 (DnaJ heat shock protein family (Hsp40) member C11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8531 in Genome Data Viewer
    Location:
    50E6-50E6; 2-69 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14256493..14258787)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10143998..10146292)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Multi drug resistance 50 Neighboring gene Heat shock protein 70 cognate 5 Neighboring gene beta1,4-N-acetylgalactosaminyltransferase A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of Drosophila beta1,4-N-acetlygalactosaminyltransferases. Haines N, et al. Glycobiology, 2005 Apr. PMID 15563714
    2. OWL1: an Arabidopsis J-domain protein involved in perception of very low light fluences. Kneissl J, et al. Plant Cell, 2009 Oct. PMID 19808946, Free PMC Article
    3. The genetic basis of adaptation to copper pollution in Drosophila melanogaster. Everman ER, et al. Front Genet, 2023. PMID 37082199, Free PMC Article
    4. A new genetic locus controlling growth and proliferation in Drosophila melanogaster. Raisin S, et al. Genetics, 2003 Jul. PMID 12871911, Free PMC Article
    5. Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex. Huynen MA, et al. Biochim Biophys Acta, 2016 Jan. PMID 26477565

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in cristae formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8531-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14256493..14258787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137101.4 → NP_610945.1  uncharacterized protein Dmel_CG8531 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610945.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0W1
      Related
      FBpp0086667
      Conserved Domains (3) summary
      COG0484
      Location:15 → 91
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:15 → 80
      DnaJ; DnaJ domain
      pfam11875
      Location:409 → 538
      DUF3395; Domain of unknown function (DUF3395)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K0W1 Q7K0W1

    Gene LinkOut

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