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    atms antimeros [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    atmsprovided by FlyBase
    Official Full Name
    antimerosprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010750
    Locus tag
    Dmel_CG2503
    See related
    AllianceGenome:FB:FBgn0010750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.113; anon-WO0172774.114; anon-WO0172774.116; Atms; CG2503; Dmel\CG2503; dPaf1; l(3)01456; l(3)02466; l(3)rK509; PAF; Paf1; PAF1
    Summary
    Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Involved in positive regulation of DNA-templated transcription. Located in euchromatin. Part of Cdc73/Paf1 complex. Is expressed in organism. Orthologous to human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See atms in Genome Data Viewer
    Location:
    82D3-82D5; 3-47.1 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4750035..4777490)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (575757..603212)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46137 Neighboring gene transforming acidic coiled-coil protein Neighboring gene mir-9384 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Coiled-coil domain containing protein 39

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence. McGurk L, et al. Hum Mol Genet, 2021 Sep 15. PMID 34077532, Free PMC Article
    2. Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Adelman K, et al. Mol Cell Biol, 2006 Jan. PMID 16354696, Free PMC Article
    3. Drosophila PAF1 Modulates PIWI/piRNA Silencing Capacity. Clark JP, et al. Curr Biol, 2017 Sep 11. PMID 28844648, Free PMC Article
    4. Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny. Buszczak M, et al. Science, 2009 Jan 9. PMID 19039105, Free PMC Article
    5. Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation. Schaerlinger B, et al. Dev Dyn, 2007 Apr. PMID 17366631

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 4753299-4757535 mobile_element_type = transposon:F{}1209
    • Loc: 4759778-4761207 mobile_element_type = transposon:hopper{}1210

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Cdc73/Paf1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Cdc73/Paf1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in euchromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    antimeros
    Names
    CG2503-PA
    CG2503-PB
    atms-PA
    atms-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4750035..4777490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275334.1 → NP_001262263.1  antimeros, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262263.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN55
      Conserved Domains (1) summary
      pfam03985
      Location:27 → 414
      Paf1; Paf1

    2. NM_141236.3 → NP_649493.1  antimeros, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649493.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN55
      Related
      FBpp0078508
      Conserved Domains (1) summary
      pfam03985
      Location:27 → 414
      Paf1; Paf1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VN55 Q9VN55

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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