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    CG3511 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3511provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035027
    Locus tag
    Dmel_CG3511
    See related
    AllianceGenome:FB:FBgn0035027
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3511
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be part of catalytic step 2 spliceosome. Is expressed in organism. Orthologous to human PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3511 in Genome Data Viewer
    Location:
    60D5-60D5; 2-107 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24571627..24574503)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20459150..20462026)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene unconventional prefoldin RPB5 interactor Neighboring gene TFIIF-interacting CTD phosphatase Neighboring gene Start1 Neighboring gene SIFamide Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene. Edgar KA, et al. Genetics, 2005 May. PMID 15744054, Free PMC Article
    2. The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Parrish JZ, et al. Neuron, 2009 Sep 24. PMID 19778508, Free PMC Article
    3. Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity. Butzlaff M, et al. Hum Mol Genet, 2015 Jul 1. PMID 25794683
    4. Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. Parkhitko AA, et al. PLoS Genet, 2021 Feb. PMID 33591981, Free PMC Article
    5. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Orian A, et al. Genes Dev, 2003 May 1. PMID 12695332, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3511-PA
    CG3511-PB
    NP_001286847.1
    NP_611935.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24571627..24574503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138091.3 → NP_611935.1  uncharacterized protein Dmel_CG3511, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611935.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960Q8, Q9W146
      Related
      FBpp0072216
      Conserved Domains (4) summary
      COG2319
      Location:75 → 312
      WD40; WD40 repeat [General function prediction only]
      cd01927
      Location:485 → 633
      cyclophilin_WD40; cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. ...
      sd00039
      Location:85 → 122
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:79 → 300
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001299918.1 → NP_001286847.1  uncharacterized protein Dmel_CG3511, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286847.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960Q8, Q9W146
      Conserved Domains (4) summary
      COG2319
      Location:75 → 312
      WD40; WD40 repeat [General function prediction only]
      cd01927
      Location:485 → 633
      cyclophilin_WD40; cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. ...
      sd00039
      Location:85 → 122
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:79 → 300
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q960Q8 Q960Q8

    Gene LinkOut

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