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    CG1603 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35683, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG1603provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033185
    Locus tag
    Dmel_CG1603
    See related
    AllianceGenome:FB:FBgn0033185
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1603
    Summary
    Predicted to enable sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1603 in Genome Data Viewer
    Location:
    43D1-43D1; 2-56 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7513846..7516390, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3401351..3403895, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene dilute class unconventional myosin Neighboring gene mitochondrial translation elongation factor Tu 2 Neighboring gene az2 Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class G Neighboring gene Origin recognition complex subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. clifford (B.4.1) , an allele of CG1603 , causes tissue overgrowth in the Drosophila melanogaster eye. Nowaskie RR, et al. MicroPubl Biol, 2023. PMID 37680216, Free PMC Article
    2. How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Ashton-Beaucage D, et al. Methods Mol Biol, 2017. PMID 27924555
    3. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article
    4. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973
    5. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1603-PA
    CG1603-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7513846..7516390 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273849.1 → NP_001260778.1  uncharacterized protein Dmel_CG1603, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260778.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1LZ24, Q95TL6
      Conserved Domains (5) summary
      COG5048
      Location:424 → 583
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:478 → 498
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam10545
      Location:202 → 287
      MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
      pfam13465
      Location:490 → 513
      zf-H2C2_2; Zinc-finger double domain
      cl23759
      Location:321 → 408
      GT1; GT1, myb-like, SANT family

    2. NM_136446.3 → NP_610290.2  uncharacterized protein Dmel_CG1603, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610290.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1LZ24, Q95TL6
      Related
      FBpp0088052
      Conserved Domains (5) summary
      COG5048
      Location:424 → 583
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:478 → 498
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam10545
      Location:202 → 287
      MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
      pfam13465
      Location:490 → 513
      zf-H2C2_2; Zinc-finger double domain
      cl23759
      Location:321 → 408
      GT1; GT1, myb-like, SANT family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LZ24 Q1LZ24
    Q95TL6 Q95TL6

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