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    CG1307 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40814, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1307provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026566
    Locus tag
    Dmel_CG1307
    See related
    AllianceGenome:FB:FBgn0026566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00004.12; Dmel\CG1307
    Summary
    Predicted to enable aminoacyl-tRNA hydrolase activity. Predicted to be active in cytosol and mitochondrion. Is expressed in adult head; adult heart; and organism. Orthologous to human PTRH2 (peptidyl-tRNA hydrolase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1307 in Genome Data Viewer
    Location:
    84A1-84A1; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6656030..6657442, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2481752..2483504, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene sungrazer Neighboring gene uncharacterized protein Neighboring gene Argininosuccinate synthase Neighboring gene TBP-associated factor 1 Neighboring gene twisted bristles roughened eye Neighboring gene O-6-alkylguanine-DNA alkyltransferase Neighboring gene labial

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fine-scale genetic mapping of a hybrid sterility factor between Drosophila simulans and D. mauritiana: the varied and elusive functions of "speciation genes". Araripe LO, et al. BMC Evol Biol, 2010 Dec 14. PMID 21144061, Free PMC Article
    2. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article
    3. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article
    4. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100
    5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables aminoacyl-tRNA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables aminoacyl-tRNA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1307-PC
    CG1307-PE
    hypothetical 23.1kd-like protein
    NP_001287202.1
    NP_649675.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6656030..6657442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300273.1 → NP_001287202.1  uncharacterized protein Dmel_CG1307, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287202.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97067, Q8MR09, Q9VI42
      UniProtKB/TrEMBL
      E1JJ73
      Conserved Domains (1) summary
      cd02430
      Location:72 → 186
      PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

    2. NM_141418.4 → NP_649675.2  uncharacterized protein Dmel_CG1307, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649675.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97067, Q8MR09, Q9VI42
      UniProtKB/TrEMBL
      E1JJ73
      Conserved Domains (1) summary
      cd02430
      Location:72 → 186
      PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JJ73 E1JJ73
    O97067.2 O97067

    Gene LinkOut

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