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    Ceacam13 CEA cell adhesion molecule 13 [ Mus musculus (house mouse) ]

    Gene ID: 69785, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ceacam13provided by MGI
    Official Full Name
    CEA cell adhesion molecule 13provided by MGI
    Primary source
    MGI:MGI:1917035
    See related
    Ensembl:ENSMUSG00000057195 AllianceGenome:MGI:1917035
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1600012K03Rik; 1600025J19Rik
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 72.5) See more
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    Genomic context

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    See Ceacam13 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17743814..17753145)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18009889..18019220)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule 11 Neighboring gene MHC I like leukocyte 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18161 Neighboring gene eukaryotic translation initiation factor pseudogene Neighboring gene CEA cell adhesion molecule 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC117613

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 13
    Names
    CEA-related cell adhesion molecule 13
    Ceacam13-C1
    Ceacam13-C2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027210.3 → NP_081486.1  carcinoembryonic antigen-related cell adhesion molecule 13 isoform 1 precursor

      See identical proteins and their annotated locations for NP_081486.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1. Isoforms 1 and 2 are the same length and differ only in their last two aa.
      Source sequence(s)
      AK005430, BY705748
      Consensus CDS
      CCDS39790.1
      UniProtKB/TrEMBL
      Q9DAY4
      Related
      ENSMUSP00000104128.2, ENSMUST00000108488.7
      Conserved Domains (2) summary
      cd05774
      Location:36 → 140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:156 → 260
      Ig; Immunoglobulin domain

    2. NM_028171.2 → NP_082447.1  carcinoembryonic antigen-related cell adhesion molecule 13 isoform 2 precursor

      See identical proteins and their annotated locations for NP_082447.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes isoform 2 and differs in the 3' UTR and coding sequence compared to variant 1. Isoforms 1 and 2 are the same length and differ only in their last two aa.
      Source sequence(s)
      AK005537
      Consensus CDS
      CCDS20866.1
      UniProtKB/TrEMBL
      Q9DAT7
      Related
      ENSMUSP00000080404.7, ENSMUST00000081703.8
      Conserved Domains (2) summary
      cd05774
      Location:36 → 140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:156 → 260
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      17743814..17753145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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