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    Psg27 pregnancy-specific beta-1-glycoprotein 27 [ Mus musculus (house mouse) ]

    Gene ID: 545925, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Psg27provided by MGI
    Official Full Name
    pregnancy-specific beta-1-glycoprotein 27provided by MGI
    Primary source
    MGI:MGI:1891359
    See related
    Ensembl:ENSMUSG00000070797 AllianceGenome:MGI:1891359
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    cea15; EG545925
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM4 (CEA cell adhesion molecule 4); CEACAM7 (CEA cell adhesion molecule 7); and PSG5 (pregnancy specific beta-1-glycoprotein 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 225.1) See more
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    Genomic context

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    See Psg27 in Genome Data Viewer
    Location:
    7 A3; 7 9.15 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18290439..18301230, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18556514..18567305, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene pregnancy-specific beta-1-glycoprotein 25 Neighboring gene STARR-seq mESC enhancer starr_18170 Neighboring gene predicted gene, 26062 Neighboring gene STARR-seq mESC enhancer starr_18171 Neighboring gene RNA (guanine-9-) methyltransferase domain containing 2 pseudogene Neighboring gene pregnancy-specific beta-1-glycoprotein 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Clone Names

    • MGC117716

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    pregnancy-specific beta-1-glycoprotein 27
    Names
    pregnancy-specific glycoprotein 27

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037168.1 → NP_001032245.1  pregnancy-specific beta-1-glycoprotein 27 precursor

      See identical proteins and their annotated locations for NP_001032245.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100351
      Consensus CDS
      CCDS20873.1
      UniProtKB/TrEMBL
      Q497W2
      Related
      ENSMUSP00000092388.4, ENSMUST00000094794.5
      Conserved Domains (4) summary
      cd05774
      Location:155 → 259
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00408
      Location:399 → 460
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:394 → 471
      IG_like; Immunoglobulin like
      cl11960
      Location:275 → 379
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      18290439..18301230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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