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    Rwdd2a RWD domain containing 2A [ Mus musculus (house mouse) ]

    Gene ID: 69519, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rwdd2aprovided by MGI
    Official Full Name
    RWD domain containing 2Aprovided by MGI
    Primary source
    MGI:MGI:1916769
    See related
    Ensembl:ENSMUSG00000032417 AllianceGenome:MGI:1916769
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rwdd2; 1700030C20Rik
    Summary
    Orthologous to human RWDD2A (RWD domain containing 2A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 18.3), cerebellum adult (RPKM 6.4) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rwdd2a in Genome Data Viewer
    Location:
    9 E3.1; 9 46.58 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (86454041..86456952)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (86571988..86574899)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 4 pseudogene Neighboring gene ubiquitin protein ligase E3D Neighboring gene DOP1 leucine zipper like protein A Neighboring gene STARR-positive B cell enhancer ABC_E9332 Neighboring gene phosphoglucomutase 3 Neighboring gene STARR-positive B cell enhancer ABC_E10572 Neighboring gene malic enzyme 1, NADP(+)-dependent, cytosolic Neighboring gene STARR-seq mESC enhancer starr_24835 Neighboring gene RIKEN cDNA A330041J22 gene Neighboring gene predicted gene, 22138

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC144625, MGC144626

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    RWD domain-containing protein 2A
    Names
    RWD domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145968.1 → NP_001139440.1  RWD domain-containing protein 2A

      See identical proteins and their annotated locations for NP_001139440.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AI848608, BC115692
      Consensus CDS
      CCDS23382.1
      UniProtKB/Swiss-Prot
      Q9D9S3
      UniProtKB/TrEMBL
      Q14BN8
      Related
      ENSMUSP00000137392.2, ENSMUST00000179212.3
      Conserved Domains (2) summary
      pfam05773
      Location:7 → 130
      RWD; RWD domain
      pfam06544
      Location:160 → 281
      DUF1115; Protein of unknown function (DUF1115)

    2. NM_001145969.1 → NP_001139441.1  RWD domain-containing protein 2A

      See identical proteins and their annotated locations for NP_001139441.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AI848608, AK006533, CJ149958, CN836837
      Consensus CDS
      CCDS23382.1
      UniProtKB/Swiss-Prot
      Q9D9S3
      UniProtKB/TrEMBL
      Q14BN8
      Related
      ENSMUSP00000139930.2, ENSMUST00000185566.7
      Conserved Domains (2) summary
      pfam05773
      Location:7 → 130
      RWD; RWD domain
      pfam06544
      Location:160 → 281
      DUF1115; Protein of unknown function (DUF1115)

    3. NM_027100.2 → NP_081376.2  RWD domain-containing protein 2A

      See identical proteins and their annotated locations for NP_081376.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AI848608, BC115691
      Consensus CDS
      CCDS23382.1
      UniProtKB/Swiss-Prot
      Q9D9S3
      UniProtKB/TrEMBL
      Q14BN8
      Related
      ENSMUSP00000034988.4, ENSMUST00000034988.10
      Conserved Domains (2) summary
      pfam05773
      Location:7 → 130
      RWD; RWD domain
      pfam06544
      Location:160 → 281
      DUF1115; Protein of unknown function (DUF1115)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      86454041..86456952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9S3.1 GenPept UniProtKB/Swiss-Prot:Q9D9S3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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