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    CG18048 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40782, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18048provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037435
    Locus tag
    Dmel_CG18048
    See related
    AllianceGenome:FB:FBgn0037435
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18048
    Summary
    Predicted to enable tRNA 2'-O-methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in organism. Orthologous to human TRMT13 (tRNA methyltransferase 13 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18048 in Genome Data Viewer
    Location:
    83E4-83E4; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6346111..6347519)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2171833..2173241)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Small ribonucleoprotein particle protein SmD2 Neighboring gene Hormone receptor 83 Neighboring gene p21-activated kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    2. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables tRNA 2'-O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA 2'-O-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tRNA methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18048-PA
    NP_649646.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6346111..6347519
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141389.4 → NP_649646.3  uncharacterized protein Dmel_CG18048 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649646.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX24, Q9VI11
      Related
      FBpp0081209
      Conserved Domains (3) summary
      pfam05206
      Location:183 → 429
      TRM13; Methyltransferase TRM13
      pfam05253
      Location:69 → 92
      zf-U11-48K; U11-48K-like CHHC zinc finger
      pfam11722
      Location:20 → 44
      zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SX24 Q8SX24

    Gene LinkOut

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