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    CHKov1 CHK domain ov1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CHKov1provided by FlyBase
    Official Full Name
    CHK domain ov1provided by FlyBase
    Primary source
    FLYBASE:FBgn0045761
    Locus tag
    Dmel_CG10618
    See related
    AllianceGenome:FB:FBgn0045761
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH03753; CG10618; Dmel\CG10618; Dro18-2; ref(3)D
    Summary
    Predicted to enable ecdysteroid 22-kinase activity. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CHKov1 in Genome Data Viewer
    Location:
    96D1-96D1; 3-87 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25323156..25329316, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21148878..21155038, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene CHK domain ov2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Host-pathogen coevolution increases genetic variation in susceptibility to infection. Duxbury EM, et al. Elife, 2019 Apr 30. PMID 31038124, Free PMC Article
    2. Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication. Magwire MM, et al. PLoS Genet, 2011 Oct. PMID 22028673, Free PMC Article
    3. The genetic architecture of resistance to virus infection in Drosophila. Cogni R, et al. Mol Ecol, 2016 Oct. PMID 27460507, Free PMC Article
    4. Detection of hard and soft selective sweeps from Drosophila melanogaster population genomic data. Garud NR, et al. PLoS Genet, 2021 Feb. PMID 33635910, Free PMC Article
    5. Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps. Garud NR, et al. PLoS Genet, 2015 Feb. PMID 25706129, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c25328927-25324412 mobile_element_type = transposon:Doc{}CHKov1[Doc1420]

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ecdysteroid 22-kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CHK domain ov1
    Names
    CG10618-PE
    CHKov1-PE
    refractory to sigma D

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25323156..25329316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104448.2 → NP_001097918.1  CHK domain ov1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q107G0, Q107I8
      Conserved Domains (1) summary
      pfam02958
      Location:41 → 325
      EcKinase; Ecdysteroid kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q107I8 Q107I8
    Q961V7 Q961V7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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