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    CG18547 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41452, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18547provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037973
    Locus tag
    Dmel_CG18547
    See related
    AllianceGenome:FB:FBgn0037973
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18547
    Summary
    Predicted to enable D-arabinose 1-dehydrogenase [NAD(P)+] activity. Predicted to be involved in dehydro-D-arabinono-1,4-lactone biosynthetic process. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18547 in Genome Data Viewer
    Location:
    87A4-87A4; 3-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11978574..11980390, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7804296..7806112, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44135 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene regulation by the lysine demethylase KDM4A in Drosophila. Crona F, et al. Dev Biol, 2013 Jan 15. PMID 23195220
    2. Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine. Zhang CH, et al. J Insect Sci, 2019 May 1. PMID 31115476, Free PMC Article
    3. Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex. Arbeitman MN, et al. G3 (Bethesda), 2016 Jul 7. PMID 27172187, Free PMC Article
    4. A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Ren J, et al. Hum Mol Genet, 2011 Sep 1. PMID 21653638, Free PMC Article
    5. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. Stobdan T, et al. PLoS One, 2019. PMID 30861021, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-arabinose 1-dehydrogenase [NAD(P)+] activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables L-galactose dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18547-PA
    NP_650138.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11978574..11980390 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141881.2 → NP_650138.1  uncharacterized protein Dmel_CG18547 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650138.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGF3
      Related
      FBpp0081980
      Conserved Domains (2) summary
      COG0667
      Location:22 → 331
      Tas; Predicted oxidoreductase (related to aryl-alcohol dehydrogenase) [General function prediction only]
      cl00470
      Location:24 → 321
      Aldo_ket_red; Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGF3 Q9VGF3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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