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    AnxB10 Annexin B10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33019, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AnxB10provided by FlyBase
    Official Full Name
    Annexin B10provided by FlyBase
    Primary source
    FLYBASE:FBgn0000084
    Locus tag
    Dmel_CG9579
    See related
    AllianceGenome:FB:FBgn0000084
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Ann; AnnB10; annexin; Annx; AnnX; ANXB10; anxX; CG9579; Dmel\CG9579
    Summary
    Enables calcium-dependent phospholipid binding activity. Predicted to be located in membrane. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in several structures, including adult head; adult heart; embryonic head sensory system; embryonic/larval dorsal vessel; and sensory nervous system primordium. Orthologous to several human genes including ANXA8 (annexin A8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See AnxB10 in Genome Data Viewer
    Location:
    19C1-19C1; 1-64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20171445..20173514, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20065478..20067547, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene PHD finger protein 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sperm-specific dynein intermediate chain 1 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the Drosophila melanogaster annexin X gene. Benevolenskaya EV, et al. DNA Cell Biol, 1995 Apr. PMID 7710691
    2. Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development. Johnston PA, et al. J Biol Chem, 1990 Jul 5. PMID 2141610
    3. New gene evolution: little did we know. Long M, et al. Annu Rev Genet, 2013. PMID 24050177, Free PMC Article
    4. Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing. Nurminsky DI, et al. Mol Cell Biol, 1998 Nov. PMID 9774695, Free PMC Article
    5. Evolutionary biology. A plastic genome. Capy P. Nature, 1998 Dec 10. PMID 9859983

    See all (68) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-dependent phospholipid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylserine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    annexin B10
    Names
    AnxB10-PA
    AnxB10-PB
    CG9579-PA
    CG9579-PB
    annexin X
    dAnnexin X

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20171445..20173514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057267.4 → NP_476615.1  annexin B10, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476615.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P22465
      Related
      FBpp0070024
      Conserved Domains (1) summary
      pfam00191
      Location:19 → 84
      Annexin; Annexin

    2. NM_001169333.2 → NP_001162804.1  annexin B10, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162804.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      E1JJR8, E8NH50, P22465, Q27586, Q9W5W5
      Conserved Domains (1) summary
      pfam00191
      Location:19 → 84
      Annexin; Annexin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22465.3 P22465

    Gene LinkOut

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