U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG5199 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40265, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG5199provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036994
    Locus tag
    Dmel_CG5199
    See related
    AllianceGenome:FB:FBgn0036994
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CUT8; Dmel\CG5199
    Summary
    Predicted to enable proteasome binding activity. Involved in proteasome localization. Colocalizes with nuclear membrane. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG5199 in Genome Data Viewer
    Location:
    77C3-77C3; 3-47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20450532..20452864, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20443632..20445964, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45176 Neighboring gene long non-coding RNA:CR43943 Neighboring gene 4-hydroxyphenylpyruvate dioxygenase Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U snoRNA host gene 8

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Regulation of nuclear proteasome by Rhp6/Ubc2 through ubiquitination and destruction of the sensor and anchor Cut8. Takeda K, et al. Cell, 2005 Aug 12. PMID 16096059
    2. Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Moshkin YM, et al. Mol Cell, 2009 Sep 24. PMID 19782028
    3. MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila. Szuplewski S, et al. Genetics, 2012 Feb. PMID 22095085, Free PMC Article
    4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    5. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nuclear protein quality control by the ubiquitin-proteasome system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear protein quality control by the ubiquitin-proteasome system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteasome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteasome localization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteasome localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    colocalizes_with nuclear membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG5199-PA
    CG5199-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20450532..20452864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275183.1 → NP_001262112.1  uncharacterized protein Dmel_CG5199, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXU1, Q9VPF1
      Conserved Domains (1) summary
      pfam08559
      Location:193 → 377
      Cut8; Cut8, nuclear proteasome tether protein

    2. NM_140970.4 → NP_649227.2  uncharacterized protein Dmel_CG5199, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649227.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXU1, Q9VPF1
      Related
      FBpp0077882
      Conserved Domains (1) summary
      pfam08559
      Location:193 → 377
      Cut8; Cut8, nuclear proteasome tether protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXU1 Q8SXU1
    Q9VPF1 Q9VPF1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools