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    CG31832 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31832provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051832
    Locus tag
    Dmel_CG31832
    See related
    AllianceGenome:FB:FBgn0051832
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AAF44911; BG:DS00929.7; Dmel\CG31832; DS00929.7; FBpp0080285
    Summary
    Predicted to enable transmembrane receptor protein tyrosine kinase activator activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human MFAP4 (microfibril associated protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31832 in Genome Data Viewer
    Location:
    35B8-35B8; 2-50 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15030928..15031750, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15030928..15031750, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43856 Neighboring gene metabotropic GABA-B receptor subtype 1 Neighboring gene uncharacterized protein Neighboring gene yellow-c Neighboring gene Cytokine induced apoptosis inhibitor 1 Neighboring gene Suppressor of Hairless

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of the fibrinogen-like domain of fibrinogen-related proteins in the mosquito, Anopheles gambiae, and the fruitfly, Drosophila melanogaster, genomes. Wang X, et al. BMC Genomics, 2005 Sep 8. PMID 16150145, Free PMC Article
    2. Evolution and potential function of fibrinogen-like domains across twelve Drosophila species. Middha S, et al. BMC Genomics, 2008 May 30. PMID 18513432, Free PMC Article
    3. Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals. de Wit E, et al. Genome Res, 2005 Sep. PMID 16109969, Free PMC Article
    4. Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Zdobnov EM, et al. Science, 2002 Oct 4. PMID 12364792
    5. Genie--gene finding in Drosophila melanogaster. Reese MG, et al. Genome Res, 2000 Apr. PMID 10779493, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane receptor protein tyrosine kinase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31832-PB
    Fibrinogen-related protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15030928..15031750 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165098.2 → NP_723894.2  uncharacterized protein Dmel_CG31832 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723894.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KT80
      Conserved Domains (1) summary
      cd00087
      Location:28 → 225
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KT80 Q7KT80

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