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    CG10064 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38761, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10064provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035724
    Locus tag
    Dmel_CG10064
    See related
    AllianceGenome:FB:FBgn0035724
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10064
    Summary
    Is expressed in several structures, including adult head; embryonic head sensory system; embryonic ventral epidermis; sense organ; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in visceral heterotaxy. Orthologous to human CFAP52 (cilia and flagella associated protein 52). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10064 in Genome Data Viewer
    Location:
    65D5-65D5; 3-18 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6965260..6967897, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6958360..6960997, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ubiquinol-cytochrome c reductase complex assembly factor 1 Neighboring gene Surfeit 1 Neighboring gene sugarless Neighboring gene Mis12 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional unknomics: Systematic screening of conserved genes of unknown function. Rocha JJ, et al. PLoS Biol, 2023 Aug. PMID 37552676, Free PMC Article
    2. Environmental chemical mediated male reproductive toxicity: Drosophila melanogaster as an alternate animal model. Tiwari AK, et al. Theriogenology, 2011 Jul 15. PMID 21356551
    3. An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. Sotillos S, et al. Dev Biol, 2010 Apr 15. PMID 20171201, Free PMC Article
    4. Identifying candidate genes affecting developmental time in Drosophila melanogaster: pervasive pleiotropy and gene-by-environment interaction. Mensch J, et al. BMC Dev Biol, 2008 Aug 8. PMID 18687152, Free PMC Article
    5. Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Sambandan D, et al. Genetics, 2006 Nov. PMID 17028343, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10064-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6965260..6967897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139808.2 → NP_648065.1  uncharacterized protein Dmel_CG10064 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648065.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4D0, Q9VS00
      Related
      FBpp0076646
      Conserved Domains (4) summary
      COG2319
      Location:280 → 652
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:366 → 650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:412 → 449
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:25 → 188
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T4D0 Q8T4D0
    Q9VS00 Q9VS00

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