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    CG12231 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32942, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12231provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031026
    Locus tag
    Dmel_CG12231
    See related
    AllianceGenome:FB:FBgn0031026
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12231
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Orthologous to human DESI2 (desumoylating isopeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12231 in Genome Data Viewer
    Location:
    18C8-18C8; 1-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19531032..19531742, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19425065..19425775, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Isocitrate dehydrogenase 3a Neighboring gene CoRest Neighboring gene uncharacterized protein Neighboring gene mir-972 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Model system identification of novel congenital heart disease gene candidates: focus on RPL13. Schroeder AM, et al. Hum Mol Genet, 2019 Dec 1. PMID 31625562, Free PMC Article
    2. Age-dependent chromosomal distribution of male-biased genes in Drosophila. Zhang YE, et al. Genome Res, 2010 Nov. PMID 20798392, Free PMC Article
    3. A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes. Zhang YE, et al. Bioinformatics, 2011 Jul 1. PMID 21551137, Free PMC Article
    4. The transcriptional response of Drosophila melanogaster to infection with the sigma virus (Rhabdoviridae). Carpenter J, et al. PLoS One, 2009 Aug 31. PMID 19718442, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12231-PA
    NP_573390.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      19531032..19531742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133162.2 → NP_573390.1  uncharacterized protein Dmel_CG12231 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573390.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ17, Q9VWH2
      Related
      FBpp0074548
      Conserved Domains (1) summary
      pfam05903
      Location:27 → 168
      Peptidase_C97; PPPDE putative peptidase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VWH2 Q9VWH2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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