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    CG32196 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317908, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32196provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052196
    Locus tag
    Dmel_CG32196
    See related
    AllianceGenome:FB:FBgn0052196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG32196
    Summary
    Predicted to enable gamma-glutamylcyclotransferase activity. Orthologous to human GGCT (gamma-glutamylcyclotransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32196 in Genome Data Viewer
    Location:
    75C7-75C7; 3-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18459464..18461024, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18452564..18454124, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44670 Neighboring gene long non-coding RNA:CR44671 Neighboring gene uncharacterized protein Neighboring gene Met75Cb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hid arbitrates collective cell death in the Drosophila wing. Garcia-Hughes G, et al. Mech Dev, 2015 Nov. PMID 26226435, Free PMC Article
    2. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    3. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    4. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables gamma-glutamylcyclotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gamma-glutamylcyclotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gamma-glutamylcyclotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32196-PB
    CG32196-PC
    NP_001262014.1
    NP_730334.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18459464..18461024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275085.1 → NP_001262014.1  uncharacterized protein Dmel_CG32196, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262014.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCW9
      Conserved Domains (1) summary
      pfam13772
      Location:31 → 129
      AIG2_2; AIG2-like family

    2. NM_168764.3 → NP_730334.2  uncharacterized protein Dmel_CG32196, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730334.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4R0, Q8IQT0
      Conserved Domains (2) summary
      cd06661
      Location:17 → 120
      GGCT_like; GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is ...
      pfam13772
      Location:72 → 170
      AIG2_2; AIG2-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PCW9 M9PCW9
    Q8IQT0 Q8IQT0

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