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    mRF1 mitochondrial translation release factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34720, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRF1provided by FlyBase
    Official Full Name
    mitochondrial translation release factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0032486
    Locus tag
    Dmel_CG5705
    See related
    AllianceGenome:FB:FBgn0032486
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5705; Dmel\CG5705
    Summary
    Predicted to enable translation release factor activity. Predicted to be involved in mitochondrial translational termination. Predicted to be located in mitochondrion. Is expressed in organism. Orthologous to several human genes including MTRF1L (mitochondrial translation release factor 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mRF1 in Genome Data Viewer
    Location:
    34A10-34A10; 2-47 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13219979..13221398)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13219979..13221398)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene small nuclear RNA U2 at 34AB b Neighboring gene uncharacterized protein Neighboring gene Ski6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. Soshnev AA, et al. Nucleic Acids Res, 2012 Jul. PMID 22406832, Free PMC Article
    2. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article
    3. The translation factors of Drosophila melanogaster. Marygold SJ, et al. Fly (Austin), 2017 Jan 2. PMID 27494710, Free PMC Article
    4. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article
    5. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Orian A, et al. Genes Dev, 2003 May 1. PMID 12695332, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables translation release factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation release factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translational termination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translational termination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial translation release factor 1
    Names
    CG5705-PA
    mRF1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13219979..13221398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135773.3 → NP_609617.1  mitochondrial translation release factor 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609617.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VK20
      Related
      FBpp0080024
      Conserved Domains (3) summary
      PRK00591
      Location:35 → 378
      prfA; peptide chain release factor 1; Validated
      pfam00472
      Location:234 → 338
      RF-1; RF-1 domain
      pfam03462
      Location:58 → 222
      PCRF; PCRF domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VK20 Q9VK20

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