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    POLDIP2 Polymerase (DNA-directed), delta interacting protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40655, updated on 9-Dec-2024

    Summary

    Official Symbol
    POLDIP2provided by FlyBase
    Official Full Name
    Polymerase (DNA-directed), delta interacting protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037329
    Locus tag
    Dmel_CG12162
    See related
    AllianceGenome:FB:FBgn0037329
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12162; Dmel\CG12162
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in error-free translesion synthesis. Predicted to be active in mitochondrial nucleoid and nucleus. Is expressed in adult head; adult heart; and embryonic/larval midgut. Orthologous to human POLDIP2 (DNA polymerase delta interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See POLDIP2 in Genome Data Viewer
    Location:
    83A4-83A4; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5467778..5469566)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1293500..1295288)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pancreatic eIF-2alpha kinase Neighboring gene Ribosomal protein L35A Neighboring gene mitochondrial ribosomal protein L44 Neighboring gene Snf5-related 1 Neighboring gene uncharacterized protein Neighboring gene Histone deacetylase 3

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in error-free translesion synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial nucleoid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial nucleoid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    polymerase (DNA-directed), delta interacting protein 2
    Names
    CG12162-PA
    CG12162-PB
    POLDIP2-PA
    POLDIP2-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5467778..5469566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141283.4NP_649540.1  polymerase (DNA-directed), delta interacting protein 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649540.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNC0
      Related
      FBpp0078329
      Conserved Domains (2) summary
      pfam04379
      Location:287369
      DUF525; Protein of unknown function (DUF525)
      cl01548
      Location:51237
      YccV-like; Hemimethylated DNA-binding protein YccV like
    2. NM_169054.2NP_730934.1  polymerase (DNA-directed), delta interacting protein 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730934.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPQ6
      Related
      FBpp0078330
      Conserved Domains (2) summary
      pfam04379
      Location:308390
      DUF525; Protein of unknown function (DUF525)
      cl01548
      Location:72258
      YccV-like; Hemimethylated DNA-binding protein YccV like