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    Ugt37D1 UDP-glycosyltransferase family 37 member D1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 53511, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt37D1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 37 member D1provided by FlyBase
    Primary source
    FLYBASE:FBgn0040260
    Locus tag
    Dmel_CG17932
    See related
    AllianceGenome:FB:FBgn0040260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC 005121C; CG17932; Dmel\CG17932; Ugt36Bc; UGT37D1
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; anterior endoderm; crystal cell primordium; embryonic/larval midgut primordium; and larval somatic muscle cell. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt37D1 in Genome Data Viewer
    Location:
    36B1-36B1; 2-53 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16799025..16801584)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16799025..16801584)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 37 member C2 Neighboring gene UDP-glycosyltransferase family 37 member E1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene midway Neighboring gene Chromosome segregation 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel TCF-binding sites specify transcriptional repression by Wnt signalling. Blauwkamp TA, et al. EMBO J, 2008 May 21. PMID 18418383, Free PMC Article
    2. Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system. Zhang CU, et al. PLoS Genet, 2014 Aug. PMID 25144371, Free PMC Article
    3. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Chen Y, et al. PLoS One, 2012. PMID 22514645, Free PMC Article
    4. Insect glycobiology: a lectin multigene family in Drosophila melanogaster. Theopold U, et al. Biochem Biophys Res Commun, 1999 Aug 11. PMID 10441526
    5. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 37 member D1
    Names
    CG17932-PA
    CG17932-PB
    CG17932-PC
    UDP-glycosyltransferase 36Bc
    Ugt36Bc
    Ugt37D1-PA
    Ugt37D1-PB
    Ugt37D1-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16799025..16801584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165193.2 → NP_724013.1  UDP-glycosyltransferase family 37 member D1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724013.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZD9, Q9VJH8
      Related
      FBpp0080469
      Conserved Domains (2) summary
      PHA03392
      Location:25 → 512
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:45 → 530
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. NM_144370.3 → NP_652627.2  UDP-glycosyltransferase family 37 member D1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652627.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZD9, Q9VJH8
      Related
      FBpp0080468
      Conserved Domains (2) summary
      PHA03392
      Location:25 → 512
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:45 → 530
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    3. NM_001299060.1 → NP_001285989.1  UDP-glycosyltransferase family 37 member D1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285989.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZD9, Q9VJH8
      Conserved Domains (2) summary
      PHA03392
      Location:25 → 512
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:45 → 530
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZD9 Q8SZD9
    Q9VJH8 Q9VJH8

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