U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BI3 cytochrome b mRNA maturase bI3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854605, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BI3
    Official Full Name
    cytochrome b mRNA maturase bI3
    Primary source
    SGD:S000007272
    Locus tag
    Q0115
    See related
    AllianceGenome:SGD:S000007272; FungiDB:Q0115; VEuPathDB:Q0115
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C, substrain: FY1679)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA binding activity. Involved in Group I intron splicing and mitochondrial mRNA processing. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in ovarian carcinoma and urinary bladder cancer. Orthologous to human MT-CYB (mitochondrially encoded cytochrome b). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BI3 in Genome Data Viewer
    Sequence:
    Chromosome: MT; NC_001224.1 (36540..40265)

    Chromosome MT - NC_001224.1Genomic Context describing neighboring genes Neighboring gene F1F0 ATP synthase subunit a Neighboring gene tRNA-Glu Neighboring gene cytochrome b mRNA maturase bI2 Neighboring gene intron-encoded RNA maturase bI4 Neighboring gene cytochrome b Neighboring gene tRNA-Ser Neighboring gene F0 ATP synthase subunit c

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001224.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nonhierarchical ribonucleoprotein assembly suggests a strain-propagation model for protein-facilitated RNA folding. Duncan CD, et al. Biochemistry, 2010 Jul 6. PMID 20533823, Free PMC Article
    2. Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase. Longo A, et al. Nat Struct Mol Biol, 2005 Sep. PMID 16116439
    3. The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. Duncan CD, et al. PLoS One, 2010 Feb 1. PMID 20126554, Free PMC Article
    4. SHAPE analysis of long-range interactions reveals extensive and thermodynamically preferred misfolding in a fragile group I intron RNA. Duncan CD, et al. Biochemistry, 2008 Aug 19. PMID 18642882, Free PMC Article
    5. Kinetic and thermodynamic framework for assembly of the six-component bI3 group I intron ribonucleoprotein catalyst. Bassi GS, et al. Biochemistry, 2003 Aug 26. PMID 12924947

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in Group I intron splicing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial mRNA processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitochondrial mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in respiratory electron transport chain IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cytochrome b mRNA maturase bI3
    NP_009317.1
    • Mitochondrial mRNA maturase; forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001224.1 Reference assembly

      Range
      36540..40265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_009317.1 cytochrome b mRNA maturase bI3 (mitochondrion) [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009317.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A0A7NYF0, Q36758, Q9ZZW7
      UniProtKB/TrEMBL
      G2HKE6
      Conserved Domains (2) summary
      cd00284
      Location:8 → 174
      Cytochrome_b_N; Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria, ...
      pfam00961
      Location:270 → 367
      LAGLIDADG_1; LAGLIDADG endonuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZZW7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools