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    MNC1 Mnc1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 1466443, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MNC1
    Official Full Name
    Mnc1p
    Primary source
    SGD:S000028736
    Locus tag
    YBR056W-A
    See related
    AllianceGenome:SGD:S000028736; FungiDB:YBR056W-A; VEuPathDB:YBR056W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Is active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MNC1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (351255..351455)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene 17-beta-hydroxysteroid dehydrogenase-like protein Neighboring gene tRNA-Gln Neighboring gene Mum2p Neighboring gene ubiquitin-specific protease UBP14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming. Zvonarev A, et al. Genes (Basel), 2023 Apr 27. PMID 37239347, Free PMC Article
    2. Transcriptome profile of yeast reveals the essential role of PMA2 and uncharacterized gene YBR056W-A (MNC1) in adaptation to toxic manganese concentration. Andreeva N, et al. Metallomics, 2017 Feb 22. PMID 28128390
    3. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Brar GA, et al. Science, 2012 Feb 3. PMID 22194413, Free PMC Article
    4. Complete DNA sequence of yeast chromosome II. Feldmann H, et al. EMBO J, 1994 Dec 15. PMID 7813418, Free PMC Article
    5. Target selection by natural and redesigned PUF proteins. Porter DF, et al. Proc Natl Acad Sci U S A, 2015 Dec 29. PMID 26668354, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
      Title: The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Mnc1p
    NP_001257668.1
    • Putative membrane protein; upregulated by toxic concentrations of heavy metal ions including Mn2+, Co2+, Ni2+, Cu2+, and Zn2+; mRNA identified as translated by ribosome profiling data; localizes to the cytoplasm, possibly in intracellular membranes; CYSTM (cysteine-rich transmembrane module) family member; partially overlaps dubious ORF YBR056C-B; YBR056W-A has a paralog, YDR034W-B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      351255..351455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001270739.1 → NP_001257668.1  TPA: Mnc1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_001257668.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      I2HB52
      UniProtKB/TrEMBL
      A6ZL00, D3UEF2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    I2HB52.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials