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    SEF1 Sef1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852214, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SEF1
    Official Full Name
    Sef1p
    Primary source
    SGD:S000000162
    Locus tag
    YBL066C
    See related
    AllianceGenome:SGD:S000000162; FungiDB:YBL066C; VEuPathDB:YBL066C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SEF1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (96669..100115, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribose phosphate diphosphokinase subunit PRS4 Neighboring gene ubiquitin-specific protease UBP13 Neighboring gene thioredoxin peroxidase PRX1 Neighboring gene Kip1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts. Gerwien F, et al. mBio, 2016 Oct 18. PMID 27795405, Free PMC Article
    2. Kluyveromyces lactis SEF1 and its Saccharomyces cerevisiae homologue bypass the unknown essential function, but not the mitochondrial RNase P function, of the S. cerevisiae RPM2 gene. Groom KR, et al. Yeast, 1998 Jan 15. PMID 9483797
    3. Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes. Scherens B, et al. Yeast, 1993 Dec. PMID 8154187
    4. Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity. Ohkuni K, et al. Genetics, 2003 Oct. PMID 14573466, Free PMC Article
    5. Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast. Fang T, et al. Genomics, 2020 Mar. PMID 31618673

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sef1p
    NP_009487.2
    • Putative transcription factor; has homolog in Kluyveromyces lactis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      96669..100115 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178306.1 → NP_009487.2  TPA: Sef1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009487.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPT5, P34228
      UniProtKB/TrEMBL
      B3LNK0, B5VDS2, C7GNA1, C8Z3T0
      Conserved Domains (2) summary
      smart00066
      Location:51 → 96
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
      pfam04082
      Location:353 → 577
      Fungal_trans; Fungal specific transcription factor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34228.4

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