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    pldA phospholipase D [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880040, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pldA
    Gene description
    phospholipase D
    Locus tag
    PA3487
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3902663..3905962)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene electron transport complex subunit A Neighboring gene electron transport complex subunit B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical characterization of a Pseudomonas aeruginosa phospholipase D. Spencer C, et al. Biochemistry, 2015 Feb 10. PMID 25565226, Free PMC Article
    2. Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Russell AB, et al. Nature, 2013 Apr 25. PMID 23552891, Free PMC Article
    3. A Pseudomonas aeruginosa type VI secretion phospholipase D effector targets both prokaryotic and eukaryotic cells. Jiang F, et al. Cell Host Microbe, 2014 May 14. PMID 24832454
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Biochemical characterization of a Pseudomonas aeruginosa phospholipase D.
      Title: Biochemical characterization of a Pseudomonas aeruginosa phospholipase D.
    2. H3-T6SS-dependent phospholipase D effector,PldB, facilitates intracellular invasion of host eukaryotic cells by activation of the PI3K/Akt pathway.
      Title: A Pseudomonas aeruginosa type VI secretion phospholipase D effector targets both prokaryotic and eukaryotic cells.
    3. virulence-associated phospholipases can serve as specific antibacterial effectors, suggesting that interbacterial interactions are a relevant factor driving the continuing evolution of pathogenesis
      Title: Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    phospholipase D
    NP_252177.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3902663..3905962
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252177.1 phospholipase D [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252177.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A367MBY7
      Conserved Domains (3) summary
      cd09104
      Location:51 → 200
      PLDc_vPLD1_2_like_1; Catalytic domain, repeat 1, of vertebrate phospholipases, PLD1 and PLD2, and similar proteins
      cd09141
      Location:600 → 894
      PLDc_vPLD1_2_yPLD_like_2; Catalytic domain, repeat 2, of vertebrate phospholipases, PLD1 and PLD2, yeast PLDs, and similar proteins
      PLN02866
      Location:461 → 1003
      PLN02866; phospholipase D
    Nucleotide Protein
    Heading Accession and Version

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