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    pilF type 4 fimbrial biogenesis protein PilF [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879170, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pilF
    Gene description
    type 4 fimbrial biogenesis protein PilF
    Locus tag
    PA3805
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4264530..4265288, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene histidine--tRNA ligase Neighboring gene 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) Neighboring gene hypothetical protein Neighboring gene 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN Neighboring gene nucleoside diphosphate kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional mapping of PilF and PilQ in the Pseudomonas aeruginosa type IV pilus system. Koo J, et al. Biochemistry, 2013 Apr 30. PMID 23547883
    2. PilF is an outer membrane lipoprotein required for multimerization and localization of the Pseudomonas aeruginosa Type IV pilus secretin. Koo J, et al. J Bacteriol, 2008 Nov. PMID 18776008, Free PMC Article
    3. Identification of a gene, pilF, required for type 4 fimbrial biogenesis and twitching motility in Pseudomonas aeruginosa. Watson AA, et al. Gene, 1996 Nov 21. PMID 8973346
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results of cellular fractionation studies indicated that PilF is the outer membrane pilotin required for the localization and multimerization of the secretin, PilQ.
      Title: PilF is an outer membrane lipoprotein required for multimerization and localization of the Pseudomonas aeruginosa Type IV pilus secretin.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables TPR domain binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pilus assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within pilus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within secretion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within type IV pilus assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within type IV pilus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within type IV pilus-dependent motility IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within type IV pilus-dependent motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type 4 fimbrial biogenesis protein PilF
    NP_252494.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4264530..4265288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252494.1 type 4 fimbrial biogenesis protein PilF [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252494.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HXJ2
      Conserved Domains (2) summary
      COG3063
      Location:2 → 252
      PilF; Tfp pilus assembly protein PilF [Cell motility, Extracellular structures]
      sd00006
      Location:38 → 65
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HXJ2.1

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