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    ladS lost adherence sensor LadS [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878890, updated on 24-Aug-2024

    Summary

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    Gene symbol
    ladS
    Gene description
    lost adherence sensor LadS
    Locus tag
    PA3974
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4453289..4455676, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene acyl-CoA dehydrogenase Neighboring gene transcriptional regulator Neighboring gene phosphomethylpyrimidine kinase Neighboring gene thiamine-phosphate pyrophosphorylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa. Chambonnier G, et al. PLoS Genet, 2016 May. PMID 27176226, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LadS HK thus forms, with the GacS/GacA TCS, a multicomponent signal transduction system with an original phosphorelay cascade, i.e. H1LadS-->D1LadS-->H2GacS-->D2GacA.
      Title: The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    lost adherence sensor LadS
    NP_252663.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4453289..4455676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252663.1 lost adherence sensor LadS [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252663.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5E5R7B2
      Conserved Domains (3) summary
      PRK11107
      Location:403 → 784
      PRK11107; hybrid sensory histidine kinase BarA; Provisional
      pfam07695
      Location:182 → 386
      7TMR-DISM_7TM; 7TM diverse intracellular signalling
      pfam07696
      Location:34 → 166
      7TMR-DISMED2; 7TMR-DISM extracellular 2
    Nucleotide Protein
    Heading Accession and Version

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