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    abu-8 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

    Gene ID: 178904, updated on 27-Dec-2024

    Summary

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    Official Symbol
    abu-8
    Official Full Name
    Activated in Blocked Unfolded protein response
    Primary source
    WormBase:WBGene00000031
    Locus tag
    CELE_C03A7.14
    See related
    AllianceGenome:WB:WBGene00000031
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in pharynx development. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abu-8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (5192995..5194608, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene glucuronosyltransferase Neighboring gene glucuronosyltransferase Neighboring gene Reverse transcriptase domain-containing protein Neighboring gene Venom polypeptide Neighboring gene TPR_REGION domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
    2. Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Sun J, et al. Science, 2011 May 6. PMID 21474712, Free PMC Article
    3. Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Haskins KA, et al. Dev Cell, 2008 Jul. PMID 18606143, Free PMC Article
    4. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
    5. Muscle-epidermis interactions affect exoskeleton patterning in Caenorhabditis elegans. Broday L, et al. Dev Dyn, 2007 Nov. PMID 17937397

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pharynx development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response
    NP_504393.1
    • Product from WormBase gene class abu;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5192995..5194608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071992.6 → NP_504393.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504393.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16511
    Nucleotide Protein
    Heading Accession and Version

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