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    fdps-1 Farnesyl pyrophosphate synthase [ Caenorhabditis elegans ]

    Gene ID: 173075, updated on 2-Nov-2024

    Summary

    Official Symbol
    fdps-1
    Official Full Name
    Farnesyl pyrophosphate synthase
    Primary source
    WormBase:WBGene00011058
    Locus tag
    CELE_R06C1.2
    See related
    AllianceGenome:WB:WBGene00011058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to be active in cytoplasm. Is expressed in germ line. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See fdps-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (11917806..11923915, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NEDD8-conjugating enzyme ubc-12 Neighboring gene Protein mago nashi homolog Neighboring gene Histone deacetylase Neighboring gene WH2 domain-containing protein;Wiskott-Aldrich syndrome protein family member Neighboring gene RRM domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dimethylallyltranstransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables geranyltranstransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in farnesyl diphosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in isoprenoid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pheromone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Farnesyl pyrophosphate synthase
    NP_493027.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11917806..11923915 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060626.7NP_493027.1  Farnesyl pyrophosphate synthase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493027.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62336
      Conserved Domains (1) summary
      cd00685
      Location:44268
      Trans_IPPS_HT; Trans-Isoprenyl Diphosphate Synthases, head-to-tail