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    cgp-1 GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178540, updated on 2-Nov-2024

    Summary

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    Official Symbol
    cgp-1
    Official Full Name
    GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein
    Primary source
    WormBase:WBGene00000480
    Locus tag
    CELE_Y38C9A.2
    See related
    AllianceGenome:WB:WBGene00000480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Orthologous to human GTPBP1 (GTP binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See cgp-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (118202..122789, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS27 Neighboring gene Pry-1 Interacting and CABIN1 Domain containing Neighboring gene Zinc finger ZPR1-type domain-containing protein;Zinc finger protein ZPR1 homolog Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
    4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation elongation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein
    NP_001300232.1
    • Confirmed by transcript evidence
    NP_001300233.1
    • Confirmed by transcript evidence
    NP_503137.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      118202..122789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070736.8 → NP_503137.1  GTP-binding protein cgp-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503137.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18905, Q9UAZ4
      Conserved Domains (4) summary
      cd04165
      Location:142 → 364
      GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
      COG5258
      Location:44 → 552
      GTPBP1; GTPase [General function prediction only]
      cd03694
      Location:373 → 459
      GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
      cd03708
      Location:465 → 551
      GTPBP_III; Domain III of the GP-1 family of GTPases

    2. NM_001313303.3 → NP_001300232.1  GTP_EFTU_D3 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ASE6
      Conserved Domains (2) summary
      cd03708
      Location:50 → 136
      GTPBP_III; Domain III of the GP-1 family of GTPases
      cl02787
      Location:1 → 44
      Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins

    3. NM_001313304.3 → NP_001300233.1  GTP_EFTU_D3 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AW00
      Conserved Domains (1) summary
      cd03708
      Location:11 → 97
      GTPBP_III; Domain III of the GP-1 family of GTPases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18905.2

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