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    orc-5 Origin recognition complex subunit 5 C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177964, updated on 2-Nov-2024

    Summary

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    Official Symbol
    orc-5
    Official Full Name
    Origin recognition complex subunit 5 C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00013857
    Locus tag
    CELE_ZC168.3
    See related
    AllianceGenome:WB:WBGene00013857
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Orthologous to human ORC5 (origin recognition complex subunit 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See orc-5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (10732832..10734588, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Calx-beta domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene G2/mitotic-specific cyclin-B1 Neighboring gene Ground-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dynamics of replication licensing in live Caenorhabditis elegans embryos. Sonneville R, et al. J Cell Biol, 2012 Jan 23. PMID 22249291, Free PMC Article
    2. PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo. Benkemoun L, et al. J Cell Biol, 2014 May 26. PMID 24841566, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA replication origin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA replication initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of origin recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Origin recognition complex subunit 5 C-terminal domain-containing protein
    NP_001255507.1
    • Confirmed by transcript evidence
    NP_001366775.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10732832..10734588 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380453.3 → NP_001366775.1  Origin recognition complex subunit 5 C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23249
      Conserved Domains (2) summary
      pfam13191
      Location:5 → 111
      AAA_16; AAA ATPase domain
      pfam14630
      Location:162 → 392
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus

    2. NM_001268578.3 → NP_001255507.1  Origin recognition complex subunit 5 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255507.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT51
      Conserved Domains (1) summary
      pfam14630
      Location:3 → 41
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus
    Nucleotide Protein
    Heading Accession and Version

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