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    W05F2.4 E3 ubiquitin-protein ligase TRIP12;SH2 domain-containing protein;Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 3896724, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W05F2.4
    Official Full Name
    E3 ubiquitin-protein ligase TRIP12;SH2 domain-containing protein;Uncharacterized protein
    Primary source
    WormBase:WBGene00021036
    Locus tag
    CELE_W05F2.4
    See related
    AllianceGenome:WB:WBGene00021036
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in body wall musculature and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W05F2.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    37
    Sequence:
    Chromosome: I; NC_003279.8 (3374776..3402864, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RRM domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cyclin-dependent kinase 2;Protein kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIP12;SH2 domain-containing protein;Uncharacterized protein
    NP_001032983.2
    • Confirmed by transcript evidence
    NP_001032984.2
    • Confirmed by transcript evidence
    NP_001249361.1
    • Confirmed by transcript evidence
    NP_001391088.1
    • Confirmed by transcript evidence
    NP_001391089.1
    • Confirmed by transcript evidence
    NP_001391090.1
    • Confirmed by transcript evidence
    NP_001391091.1
    • Confirmed by transcript evidence
    NP_001391092.1
    • Confirmed by transcript evidence
    NP_001391093.1
    • Confirmed by transcript evidence
    NP_001391094.1
    • Confirmed by transcript evidence
    NP_001391099.1
    • Confirmed by transcript evidence
    NP_001391100.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3374776..3402864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001037894.5 → NP_001032983.2  E3 ubiquitin-protein ligase TRIP12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001032983.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SF97, G4SFA4, G4SFA5
      Conserved Domains (1) summary
      pfam12200
      Location:677 → 727
      DUF3597; Domain of unknown function (DUF3597)

    2. NM_001262432.4 → NP_001249361.1  SH2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001249361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SFA7, Q1XFX9
      Conserved Domains (1) summary
      PRK14907
      Location:147 → 219
      rplD; 50S ribosomal protein L4; Provisional

    3. NM_001037895.5 → NP_001032984.2  SH2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001032984.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SFA6, G4SFA7
      Conserved Domains (1) summary
      PRK14907
      Location:119 → 191
      rplD; 50S ribosomal protein L4; Provisional

    4. NM_001404255.1 → NP_001391094.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QBM9, G4SFA4

    5. NM_001404256.1 → NP_001391090.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QD04, G4SFA4

    6. NM_001404257.1 → NP_001391092.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QAV6, G4SFA4

    7. NM_001404258.1 → NP_001391093.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QD20, G4SFA4

    8. NM_001404259.1 → NP_001391089.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QEY9, G4SFA4

    9. NM_001404260.1 → NP_001391091.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QBN7, G4SFA4

    10. NM_001404261.1 → NP_001391088.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QAT5, G4SFA4

    11. NM_001404262.1 → NP_001391099.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QD09

    12. NM_001404263.1 → NP_001391100.1  Uncharacterized protein CELE_W05F2.4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QBP9
    Nucleotide Protein
    Heading Accession and Version

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