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    mtch-1 Mitochondrial carrier [ Caenorhabditis elegans ]

    Gene ID: 174207, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mtch-1
    Official Full Name
    Mitochondrial carrier
    Primary source
    WormBase:WBGene00018395
    Locus tag
    CELE_F43E2.7
    See related
    AllianceGenome:WB:WBGene00018395
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane and mitochondrion. Is expressed in several structures, including enteric muscle; intestine; nervous system; pharynx; and rectal epithelium. Orthologous to human MTCH1 (mitochondrial carrier 1) and MTCH2 (mitochondrial carrier 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mtch-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (7372615..7374166, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Peptidylprolyl isomerase Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene RNA polymerase Rpb4/RPC9 core domain-containing protein Neighboring gene Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of MTCH-1 suppresses age-related proteostasis collapse through the inhibition of programmed cell death factors. Aman Y, et al. Cell Rep, 2022 Nov 22. PMID 36417880
    2. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
    3. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
    4. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    5. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial carrier
    NP_001364693.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7372615..7374166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001377817.2 → NP_001364693.1  Mitochondrial carrier [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYJ5
    Nucleotide Protein
    Heading Accession and Version

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